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Truth about Keto diet and ketosis:
From a 40,000 ft view of the body's entire physiology.
Understanding ALL of biochemistry, the physiology of the human body is necessary before beginning.
For example:
Ketosis—a metabolic state where the body burns fat for fuel, producing ketones instead of relying primarily on glucose. It delivers miraculous short-term benefits that make it seem like a miracle for many, especially those starting from a standard modern diet filled with poor quality foods, and poisons, over-ladened with excessive amounts of refined sugar.
However, sustained ketosis is not aligned with human physiology’s long-term needs, particularly in vulnerable populations like those with neurodegeneration or chronic disease, or in severe disease states .
1. Most people adopting keto drastically cut refined sugars, processed foods, GMO corn products (high in inflammatory omega-6s), glyphosate-laden wheat, and conventionally grown produce sprayed with atrazine, pesticides, and herbicides. These chemicals disrupt gut integrity, promote systemic inflammation, and burden detoxification pathways. By removing them—even temporarily—inflammation drops sharply. The “glow” many report isn’t purely from ketones; it’s largely from halting continuous toxic exposure.
2. Ketosis mimics caloric restriction, ramping up autophagy—the cellular cleanup process that recycles damaged components and reduces oxidative stress. Combined with lower toxin intake, this creates a profound sense of clarity, energy, and symptom relief. People notice reduced bloating, brain fog, and pain because the body finally gets a break from processing daily chemical assaults.
3. High intake of healthy fats and quality animal proteins supplies abundant building blocks: cholesterol and phospholipids for cell membranes, hormone production, and bile production, amino acids for muscle repair, collagen synthesis, and myelin sheath integrity. In a nutrient-deprived modern diet, this sudden influx supports rapid tissue rebuilding, contributing to improved strength, recovery, and neurological stability early on.
These combined effects create a compelling “honeymoon phase” that convinces many ketosis is the ultimate cure—especially when pushed by influencers as the “new thing”, as everyone is searching for something that “works” for how bad they feel.
But these gains will eventually plateau or reverse as the body adapts and restrictions reveal the costs in long term.
Human physiology was designed for flexibility—seamlessly switching fuels—not permanent ketosis, a SURVIVAL mechanism for famine.
Chronic restriction imposes trade-offs that compound over months and years, especially in severe diseased states.
4. Ketosis is naturally diuretic, flushing electrolytes (sodium, potassium, magnesium) as glycogen depletes and water is released. Even in adapted ketosis, higher protein/fat metabolism increases urinary mineral loss. Keto’s restricted food variety—limiting fruits, roots, and CLEAN whole wheat—makes it nearly impossible to consume therapeutic doses needed to refill depleted stores.
5. Neurodegenerative and severe disease state people START with unbalanced sodium and potassium, and low magnesium, zinc, and selenium; chronic deficiency impairs ATP production, antioxidant defenses, and neuronal signaling. Supplements help short-term but do not match the synergistic, bioavailable delivery from whole food, leading to progressive deficits: fatigue, cramps, arrhythmias, and worsened neurodegeneration.
Those that don’t supplement high doses of whole food derived minerals are not getting enough therapeutically and would have to spend hundreds of dollars trying to acquire from the current market - which unironically derives these minerals and nutrients FROM FRUIT and herb bearing seed. LOL
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6. High fat demands robust bile production and liver processing. In disease states—where livers are already struggling to conjugate and excrete toxins (heavy metals, pesticides, metabolic waste)—this added load taxes the liver’s abilities, increases fatty liver infiltration, cholestasis, and further detox backlog. Kidneys face higher filtration demands from protein metabolites and ketones, increasing demand and stress in compromised systems desperately trying to clear accumulated burdens.
7. REALLY IMPORTANT: Strict keto severely limits fiber and prebiotics, starving beneficial gut bacteria. This promotes dysbiosis—loss of microbial diversity and overgrowth of pro-inflammatory species. A healthy microbiome is ESSENTIAL for:
• Binding and excreting toxins (preventing liver recirculation).
• Producing short-chain fatty acids that support gut barrier and oxidative states that cause extensive damage.
• Metabolizing heavy metals and misfolded proteins.
In neurodegeneration (Alzheimer’s, Parkinson’s), toxin backlog is already central—misfolded proteins cross the gut-brain axis, and heavy metals exacerbate mitochondrial damage. Low-fiber ketosis compounds this by slowing transit, allowing greater toxin reabsorption and perpetuating neuroinflammation.
8. Nearly all chronic diseases involve gut motility issues, leaky barrier, or inflammation. Without fiber’s bulking and lubricating effects, constipation worsens, further clogging an already sluggish GI tract and amplifying toxin retention.
9. Neurodegneration patients often exhibit mitochondrial damage and dysfunction, and brain glucose hypometabolism. While ketones provide alternative fuel short-term, severely damaged mitochondria struggle to utilize them efficiently. More critically, mitochondrial biogenesis (creating new, healthy mitochondria) requires specific plant-derived activators via pathways like PGC-1α and AMPK:
• Resveratrol (grapes, berries) – potent PGC-1α stimulator.
• Quercetin (apples, onions, berries) – enhances mitochondrial number and function.
• EGCG (green tea) – boosts biogenesis and neuroprotection.
• Curcumin (turmeric) and ursolic acid (apple peels, holy basil) – support renewal and reduce oxidative damage.
Strict keto restricts these sources, hindering true mitochondrial repair and leaving patients reliant on faulty existing organelles.
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Lastly, in Genesis 1:29, God says directly:
“See, I have given you every herb that yields seed which is on the face of all the earth, and every tree whose fruit yields seed; to you it shall be for food.”
Note the imperative “shall be”—not a suggestion (“can be”) but a divine mandate. This pre-fall diet was entirely fruit and herb-based: seed-bearing herbs, fruits, and trees—rich in the very phytonutrients, fiber, minerals, and medicinal compounds discussed above. These foods were designed as our foundational sustenance and “medicine,” supplying everything needed for vibrant life in a perfect world: detoxification support, mitochondrial vitality, toxin protection, and structural cofactors - parts and tools to rebuild. Great that you show up with wood and concrete. You’re gonna need power tools, nuts and bolts to build tho.
Animal foods were only permitted post-fall (Genesis 9:3), as an accommodation to a cursed, depleted earth requiring fleshly materials and supplies necessary to rebuild flesh for survival amid sin, decay, and shortened lifespan. Meat and fat excel for structural rebuilding in our imperfect state—but we still need the fruit and herb bearing seed as our “medicine”.
Mike