The way the media pushes a diabetes medication for weight loss now is crazy work.
The side effects and long term harm Ozempic causes is insane, all for the weight to come back once you stop taking it.
Serious risks and warnings:
• Boxed (black-box) warning for thyroid C-cell tumors: Semaglutide caused these in rodents at clinically relevant exposures. It is unknown whether this applies to humans (human relevance not established). It is contraindicated with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Large human observational data have not shown a clear significant increase in thyroid cancer risk. dailymed.nlm.nih.gov
• Acute pancreatitis (including rare severe/fatal cases): Discontinue if suspected (persistent severe abdominal pain, sometimes radiating to the back, with or without nausea/vomiting). dailymed.nlm.nih.gov
• Acute gallbladder disease (gallstones/cholelithiasis, cholecystitis): Higher incidence linked partly to weight loss. novomedlink.com
• Acute kidney injury: Often secondary to dehydration from severe GI symptoms (nausea/vomiting/diarrhea); monitor kidney function, especially early on. novomedlink.com
• Diabetic retinopathy complications: Reported in some trials; monitor patients with a history of it. dailymed.nlm.nih.gov
• Hypoglycemia: Higher risk if combined with insulin or sulfonylureas.
• Severe GI issues: Including postmarketing reports of gastroparesis (stomach paralysis), ileus, intestinal obstruction, or severe constipation. Not recommended in severe gastroparesis; labels have been updated to highlight these. drugs.com
• Rare vision risk: Non-arteritic anterior ischemic optic neuropathy (NAION), a cause of sudden vision loss, has been very rarely associated (estimates around 1 in 10,000 or a possible roughly twofold relative increase in some analyses); UK/EU product information notes this. gov.uk
• Other: Serious allergic reactions (anaphylaxis, angioedema); increased risk of pulmonary aspiration during anesthesia/sedation due to delayed gastric emptying; possible contributions to muscle loss or modest bone-density changes with substantial weight loss (more related to the weight loss itself than a unique drug effect in many cases).
ITS NOT WORTH IT PEOPLE, get healthy the right way!!
Mike
The side effects and long term harm Ozempic causes is insane, all for the weight to come back once you stop taking it.
Serious risks and warnings:
• Boxed (black-box) warning for thyroid C-cell tumors: Semaglutide caused these in rodents at clinically relevant exposures. It is unknown whether this applies to humans (human relevance not established). It is contraindicated with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Large human observational data have not shown a clear significant increase in thyroid cancer risk. dailymed.nlm.nih.gov
• Acute pancreatitis (including rare severe/fatal cases): Discontinue if suspected (persistent severe abdominal pain, sometimes radiating to the back, with or without nausea/vomiting). dailymed.nlm.nih.gov
• Acute gallbladder disease (gallstones/cholelithiasis, cholecystitis): Higher incidence linked partly to weight loss. novomedlink.com
• Acute kidney injury: Often secondary to dehydration from severe GI symptoms (nausea/vomiting/diarrhea); monitor kidney function, especially early on. novomedlink.com
• Diabetic retinopathy complications: Reported in some trials; monitor patients with a history of it. dailymed.nlm.nih.gov
• Hypoglycemia: Higher risk if combined with insulin or sulfonylureas.
• Severe GI issues: Including postmarketing reports of gastroparesis (stomach paralysis), ileus, intestinal obstruction, or severe constipation. Not recommended in severe gastroparesis; labels have been updated to highlight these. drugs.com
• Rare vision risk: Non-arteritic anterior ischemic optic neuropathy (NAION), a cause of sudden vision loss, has been very rarely associated (estimates around 1 in 10,000 or a possible roughly twofold relative increase in some analyses); UK/EU product information notes this. gov.uk
• Other: Serious allergic reactions (anaphylaxis, angioedema); increased risk of pulmonary aspiration during anesthesia/sedation due to delayed gastric emptying; possible contributions to muscle loss or modest bone-density changes with substantial weight loss (more related to the weight loss itself than a unique drug effect in many cases).
ITS NOT WORTH IT PEOPLE, get healthy the right way!!
Mike
